cees dekker - An Overview
cees dekker - An Overview
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Rotary movement of DNA rotors on nanopores. Leading row: Uncooked movie on the Cy5 channel of every rotor. Center row: corresponding solitary-particle localization results of both equally ends of your DNA rotors. The placement of the current frame is marked as orange and blue dots, and the trajectory of the 10 frames prior to The existing body is demonstrated as strong lines.
Our team scientific tests bacterial mobile division and is particularly aiming to represent a ‘bottom up biology’ in synthetic cells which can autonomously divide. Our most important fascination lies in cell division, chromatin structure, and spatial control.
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Regrettably, For some time right after Iijima’s report, the creation of thoroughly clean nanotubes was cumbersome. In 1996, having said that, the group of Richard Smalley at Rice College managed to produce solitary-walled carbon nanotubes at substantial generate. Shortly just after, I contacted Smalley, and we chose to join forces to measure the transportation by way of a one carbon nanotube.
We produce level-of-care diagnostics exam of neglected tropical disorders within just source-limited configurations, based upon Crspr/Cas9 detecting of pathogen’s DNA in human body fluids.
From the yrs pursuing these discoveries, my investigation passions shifted to biophysics and nanobiology, and I turned a lot less involved with the development of nanotube electronics. The focus of numerous scientists in the field also shifted to graphene (exactly where, funnily enough, the main graphene ribbons ended up referred to as ‘nanotubes which are cut open up along their length’) just after the invention of the two-dimensional product in 2004.
Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis https://www.ceesdekker.net from DNA supercoiling research of nucleosomes and DNA repair proteins to DNA translocation by way of nanopores. Just lately his study has centered on finding out cell division with microbes on chip, when his final interest is during the route of recognizing artificial cells.
2000, discovery that nanotubes can have incredible huge latest densities; resolved the controversial concern of Digital transportation via DNA molecules by measurements of insulating habits at The one molecule level; and demonstration of an AFM procedure for single-molecule manipulation of nanotubes
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Dekker begun his investigation on single carbon nanotubes in 1993 when he arrange a different line of analysis to study electrical transportation via one organic molecules among nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was realized inside a collaboration with the team of Nobel laureate Richard Smalley. STM and nanolithography methods ended up used to reveal that these nanotubes are quantum wires at The only-molecule level, with remarkable physical Houses.
Testing pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion against roadblock-traversal experiments
1999, to start with measurement on the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for just a new Luttinger description of interacting electrons in nanotubes
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
The biophysicist from Delft – who has long been One of the more cited experts during the Netherlands For several years – can take his duty to contribute to the rationalization and popularisation of his get the job done with the border of physics and biology really critically and frequently seems while in the media; if not to talk about his work, then about the connection amongst science and his Christian faith.